Oral squamous carcinoma is one of the more common types of oral cancer. The severity of squamous oral cancer can be determined by factors such as staging and the patient’s own condition. It can be categorized into highly differentiated, moderately differentiated and lowly differentiated. Highly differentiated squamous carcinoma, as opposed to will be less severe. Oral squamous carcinoma is the most common type of oral cancer. Oral cancer can be triggered due to various factors such as tobacco, ethanol, poor oral hygiene, occupational exposures, and infections. The severity of oral squamous carcinoma type needs to be decided according to the differentiation and the patient’s own condition. Squamous carcinoma is generally categorized as highly differentiated, moderately differentiated and poorly differentiated. Highly differentiated is less severe compared to other differentiation. Patients with additional oral cavity are recommended to be actively treated. Drug treatment, surgical treatment, radiotherapy and chemotherapy can be carried out. Drug treatment is commonly used is cetuximab. Surgical treatment can be taken such as lesion excision. Chemotherapy and radiotherapy can be used for preoperative and postoperative adjuvant treatment, patients need to use drugs according to the doctor’s guidance, do not use their own medicine.