Polivi refers to clopidogrel bisulfate, which can be taken with pantoprazole. Because clopidogrel bisulfate and pantoprazole when taken together, there is no evidence that other drugs to inhibit gastric acid secretion, such as H2 blockers, (excluding the CYP2C19 inhibitor cimetidine) or antacids interfere with the antiplatelet activity of clopidogrel, the best way to take the drug is to follow the instructions of the doctor. Clopidogrel bisulfate is a platelet aggregation inhibitor that inhibits platelet aggregation. The drug can be used to prevent the formation of atherosclerotic thrombi, and overdosage can lead to bleeding as well as bleeding complications. The drug is contraindicated in patients with pathologically active bleeding, pregnant and lactating women. Pantoprazole is a proton pump inhibitor with the ability to inhibit gastric acid secretion, and is mainly used to treat peptic ulcer and other diseases. However, it is necessary to avoid taking Clopidogrel and Omeprazole at the same time, because Omeprazole inhibits CYP2C19 activity, which can affect the metabolism of Clopidogrel into active metabolites. In the event of serious adverse reactions such as cardiac arrhythmia, decreased granulocytes, altered renal function, skin rash and other allergic reactions, seek immediate medical attention.