There is no treatment for blisters on the soles of the feet that get better quickly, and for small blisters, general treatment is usually performed. When the blister is large, the symptoms are more obvious, may need to carry out blister aspiration and other treatments. 1. General treatment: the soles of the feet are only small blisters, usually less than 1cm in diameter, and the clinical symptoms are not obvious, the main general treatment should be reasonable rest, change the appropriate shoes and socks, avoid standing and walking for a long time, and wait for the blisters to be absorbed by themselves. 2. medication: after the blisters on the soles of the feet, the diameter of the blisters is larger than 1cm, can be operated by the doctor for drainage, and pay attention to clean and disinfect, avoid infection. In the drug treatment, should follow the doctor’s instructions reasonable use of drugs, do not self-medication.