Itchy skin in menopausal women is caused by lower levels of estrogen in the body, decreased sebum secretion, and a large loss of skin moisture and collagen. Patients can be treated with general treatment, oral medication, and topical medication. 1. General treatment: Reduce the frequency of bathing, use moisturizing and less irritating skin care products to keep the skin moist and reduce itching due to dryness. 2. Oral medication: It is recommended that patients with severe itching symptoms take antihistamines (such as cetirizine, etc.) for anti-itching treatment; in addition, patients can take appropriate vitamin supplements (vitamin C, vitamin B, etc.). 3. Topical medication: patients can use glycerin or 10% urea cream to keep the skin moisturized; for those with secondary bacterial infection, antibiotic cream (mupirocin ointment, etc.) can be used externally. It is recommended that menopausal patients with severe itching go to the dermatology department of regular hospitals, and follow the doctor’s instructions under the guidance of professional doctors.