Brain atrophy in 80 year olds does not affect life expectancy in some patients and affects life expectancy in others, mainly related to the cause of the disease. Brain atrophy is related to aging, heredity, disease and many other causes, and different causes have different effects on life expectancy. If brain atrophy in an 80-year-old man is caused by natural aging, it generally does not affect normal life expectancy. If it is caused by Alzheimer’s disease, it will have a certain impact on the patient’s life expectancy, and the general survival time is 5 to 10 years, and a few patients can survive for 10 years or for a longer period of time. If the cerebral atrophy is caused by cerebrovascular disease, and has affected the patient’s own activities, is bedridden, then it will also affect the life expectancy, mostly due to lung infection death. Patients with cerebral atrophy in 80-year-olds need to receive regular treatment as soon as possible to control the development of the disease.