Glaucoma is one of the serious blindness-causing eye diseases, and the number of blind people with glaucoma in China accounts for 5.3%-21% of the blind. Among the primary glaucoma, acute angle-closure glaucoma is one of the major eye diseases that occur in middle-aged and elderly people and severely damage their visual health. A typical acute attack is characterized by a rapid onset, severe eye distension, blurred vision and ipsilateral migraine, accompanied by systemic symptoms such as nausea, vomiting, increased blood pressure, loss of appetite and even fever. If a patient is first seen in the emergency department or internal medicine department and has systemic symptoms, and the physicians in these departments lack the relevant knowledge, it is easy to misdiagnose and delay treatment. Patients with glaucoma are often elderly, and patients with acute attacks of acute closure are often accompanied by headache, some even severe eye pain and headache, due to the unique manifestations of the eye. Patients with glaucoma who have a history of hypertension in the past, when symptoms such as unbearable headache, eye distension, nausea and vomiting occur, and blood pressure is induced by emotional tension and painful stimulation, they often think that cerebrovascular disease recurs and ignore the eye symptoms. They go directly to the internal medicine or emergency department, leading to misdiagnosis.