Shoulder pain at the age of fifty may be caused by trauma, frozen shoulder, cervical spondylosis, internal organ disease and other factors. 1. Trauma: the shoulder suffered an external blow, resulting in local bone or soft tissue damage, will cause shoulder pain, accompanied by swelling and subcutaneous bruising, and the pain is more intense. 2. Frozen shoulder: it may be related to the degeneration of soft tissues of the shoulder joint, prolonged over-exercise, prolonged heavy physical labor and other factors, which may lead to aseptic inflammation of the shoulder joint, which will cause shoulder pain, and in severe cases, it will also lead to limited shoulder activities. 3. Cervical spondylosis: degenerative joint changes and prolonged bowing of the head may induce cervical spondylosis, which may cause compression of the nerves innervating the upper limbs, which may easily cause shoulder pain, accompanied by neck pain, radiating pain in the upper limbs and numbness of the upper limbs and other symptoms. 4. Visceral lesions: shoulder pain may also be associated with visceral lesions, such as lung tumors, gallbladder disease, etc., which may lead to radiating and involving pain in the shoulder area. Shoulder pain at the age of fifty, it is recommended to consult a doctor for a detailed examination, to clarify the specific causes, and under the guidance of the doctor to carry out reasonable treatment, to avoid delaying the condition.