Symptoms and dangers of gallbladder thickening are determined by the specific cause of the condition. Gallbladder thickening can be caused by cholecystitis, gallbladder myxedema, gallbladder cancer, and other causes. The dangers include gallbladder necrosis, suppuration, perforation, and cancer risk. 1. Cholecystitis: Due to repeated inflammatory stimulation, it can lead to proliferation of gallbladder wall, which will cause thickening of gallbladder. Its symptoms are mainly pain in the right upper abdomen, nausea, loss of appetite, jaundice and so on. The dangers include gallbladder necrosis, suppuration, perforation and so on. 2. Gallbladder adenomyosis: due to inflammatory stimulation and irregular contraction of the gallbladder, it will lead to the proliferation of the gallbladder wall and part of the gallbladder smooth muscle, resulting in thickening of the gallbladder. More sensitive patients may have symptoms such as mild abdominal pain in the early stage, and with the development of the disease, abdominal pain, nausea, vomiting, jaundice, fever and so on. Without timely treatment, the main danger is the risk of cancer. 3. Gallbladder cancer: gallbladder cancer can lead to the appearance of new organisms in the gallbladder, causing uneven thickening of the gallbladder. Its symptoms include pain in right upper abdomen, indigestion, jaundice, fever, and the appearance of mass in right upper abdomen. The main danger is that it seriously affects the survival as well as the quality of life of the patient and needs to be treated as early as possible. In the case of gallbladder thickening, you need to find out the specific cause in time and receive treatment as soon as possible to avoid aggravation of the condition.