Tuberculosis and diabetes are mutually influential and causative when they coexist, so the two diseases must be treated simultaneously. Since diabetes mellitus has a greater impact on tuberculosis, the first step in treatment is to actively control diabetes mellitus. The treatment of diabetes includes comprehensive treatment such as diet control, appropriate exercise and reasonable application of glucose-lowering drugs, etc. Unlike the treatment of simple diabetes, the diet control can be relaxed appropriately, and the total calorie and protein intake should be increased moderately compared with that of simple diabetes. application or even as the first choice, and strive to control blood glucose as soon as possible in the short term to promote the improvement of tuberculosis. The control target of blood sugar level can be relaxed for frail and old patients, and the chemotherapy principle of anti-tuberculosis treatment is the same as that of simple tuberculosis, which must follow the principle of early combination, moderate, regular and full chemotherapy, but the course of treatment should be longer than that of simple tuberculosis, which is generally 9-12 months, and can be extended to about one and a half years if necessary.