Hepatitis E vaccination does not usually provide lifelong immunity. Hepatitis E vaccine, or hepatitis E vaccine, is an important means of preventing hepatitis E. The vaccine stimulates the body to produce IgG antibodies to the hepatitis E virus. The vaccine stimulates the body to produce IgG antibodies to the hepatitis E virus, which provides immunity against hepatitis E. In normal life, there is metabolism and therefore a gradual decrease in the number of antibodies. In normal life, due to the body’s metabolism, the antibody will gradually decrease, so the protection time of hepatitis E antibody is different for different people, and the duration of antibody in the body also has individual differences. Therefore, hepatitis E vaccination will not provide lifelong immunity. Patients are advised to go to regular hospitals and take hepatitis E vaccination under the correct operation of doctors. Transient fever, headache and fatigue may occur after vaccination, which usually disappear on their own and do not need treatment.