Pheochromocytoma is a relatively rare tumor, and clinical studies have shown that less than 50% of pheochromocytomas are diagnosed, so there is no set time for detection. Pheochromocytoma can occur at any age, with its peak incidence at 30-50 years of age and no significant difference between male and female genders. Clinical manifestations are diverse, paroxysmal hypertension is the characteristic manifestation of pheochromocytoma, while headache, palpitation, and excessive sweating are the most common accompanying symptoms of hypertensive episodes in patients with pheochromocytoma. However, clinically, most patients have atypical clinical manifestations, and some of them are even asymptomatic, and even if they have hypertension, the manifestations of elevated blood pressure are various, so it brings difficulties to the early diagnosis of pheochromocytoma. Patients with paroxysmal hypertension with headache, palpitations, excessive sweating triad and postural hypotension should be screened, which can promote the early detection of pheochromocytoma, and the specific treatment should be carried out under the guidance of physicians.