Genital herpes is a recurrent disease caused by herpes simplex virus (HSV) infection of the skin and mucous membranes of the genital and anal regions of the urinary tract, and is a common sexually transmitted disease. The source of infection for genital herpes is the genital HSV-infected person. Subclinically infected or asymptomatic detoxified persons, patients with unrecognized symptoms or atypical genital herpes are the main infectious agents of genital herpes. Asymptomatic infections and intervals of recurrent genital herpes recurrence can have asymptomatic detoxification, and their transmission is more dangerous. Sexual behavior factors such as the number of sexual partners, age at first intercourse and years of sexual activity, whether the cervix is protected or not, sexual orientation, frequency of sexual intercourse, and mode of intercourse are associated with the transmission and prevalence of genital herpes. HSV infection of the genital skin mucosa is often latent in the sacral nerve root region, and this latent infection is the underlying cause of genital herpes recurrence. When oral and lip HSV-1 infection is present first, even if genital HSV-2 infection occurs, its first episode is less symptomatic and less likely to recur. Recurrent genital usually decreases in number of episodes as the duration of the disease increases. Humans are naturally susceptible to HSV, but not everyone who is infected develops typical genital herpes. The occurrence of genital herpes depends on both host and viral factors and can manifest as latent infection, subclinical infection, and typical genital herpes. Eighty percent of so-called subclinical HSV-2 infections are actually symptomatic, but the symptoms are mild or atypical and are ignored by the doctor or patient. HSV can infect the fetus through the placenta (intrauterine HSV infection) and can also cause neonatal HSV infection. The risk of transmission of primary genital herpes to the fetus is considerably higher than that of recurrent genital, and this risk (transmission rate) is 20-50% and 0-8%, respectively. Primary genital herpes in pregnant women is associated with spontaneous abortion, intrauterine growth retardation, preterm delivery, low birth weight and congenital HSV infection in the infant, and even causes fetal death. Primary infection at different times of life leads to outcomes that are not entirely consistent. Recent studies have shown that recurrent genital herpes occurring during pregnancy is not associated with an abnormal outcome of pregnancy. Serologic testing cannot distinguish between orofacial or genital infections. The current main therapeutic agents include acyclovir, famciclovir, and valacyclovir tablets. Asymptomatic or subclinical genital HSV infections generally do not require drug therapy.