High density foci in the vena cava fossa in the mediastinum are usually seen as tumors, nodular calcifications, etc. 1. Mediastinal tumor: High density foci of vena cava fossa in the mediastinum may be mediastinal tumors, which are cancerous lesions with high density in the mediastinum, and are tumors occurring around the superior vena cava located in the mediastinum. There are many types of tumors, and the specific classification of tumors can be clarified by means of puncture pathology examination, etc. The prognosis of different tumors varies. Early benign tumors usually have no obvious symptoms, and malignant tumors in the mediastinal vena cava fossa have serious invasion of the surrounding tissues and relatively poor prognosis. If you suspect a tumor, you should improve relevant examination such as CT as soon as possible for further active treatment. 2. Nodal calcification: it is usually the calcification of lymph nodes around the vein, which is mostly caused by lymph node tuberculosis and inflammation. Patients can be treated with intravenous antibiotics, which can effectively control the infection. Smaller nodules can be self-absorbed and generally have no effect on the human body. Imaging abnormalities, but also need to be combined with clinical manifestations and other comprehensive judgment, discomfort is recommended to consult a doctor in a timely manner.