When lung infection occurs after esophageal cancer surgery, broad-spectrum antibiotics should be given to control the infection in time, and at the same time, relevant examination should be done to find out the causative organisms, and then sensitive antibiotics should be given to treat it. Esophagus is located in the chest cavity, so the surgical treatment of esophageal cancer is easy to damage human lungs, some patients are easy to develop lung infection after surgery, generally speaking, first of all, broad-spectrum antibiotics should be given to control lung infection, and at the same time, timely blood sampling, blood culture, sputum culture and drug sensitivity test should be done, and according to the results of the test, sensitive antibiotics such as amoxicillin and cephalosporin should be chosen. For cough, sputum, fever and other symptoms caused by lung infection, drugs should be given in time to stop cough, dissolve sputum, reduce fever and other symptomatic treatments. Once lung infection occurs after esophageal cancer surgery, patients should go to the hospital in time and get standardized treatment from professional doctors.