Pale and bloodless face may be caused by physiological factors such as mental tension and overwork, or it may be caused by anemia and leukemia. 1. Physiological factors: usually the patient is usually in a state of mental tension or overwork, may lead to pale and bloodless, is a normal physiological phenomenon. 2. Anemia: usually due to excessive destruction of red blood cells, blood loss, insufficient or reduced production of red blood cells and other conditions, but also with chronic diseases, dietary imbalance and other factors. Patients often appear skin and mucous membrane pale phenomenon, which can be manifested as pale and bloodless. And some patients may also have symptoms such as dizziness, shortness of breath, rapid heart rate, and lack of food. It is common in iron deficiency anemia, megaloblastic anemia, aplastic anemia and so on. 3. Leukemia: the cause of this disease is still unclear, and it is mostly considered to be related to physical, chemical, genetic, immune function, bad habits and other factors. Generally, patients with chronic leukemia may have pale face, enlarged spleen, swollen lymph nodes and so on. And some patients may also be accompanied by fatigue, night sweats, weight loss and other phenomena. It is recommended that when patients have the symptom of pale and bloodless face, they should first exclude physiological factors, and if it is caused by disease, they should seek medical treatment in time.