Rheumatoid arthritis has a genetic predisposition, but is not necessarily passed on to children. Rheumatoid arthritis is a systemic autoimmune disease that mainly involves peripheral joints. The specific cause of the disease is not yet completely clear, and it may be closely related to heredity, the environment, smoking and other factors, and it is known that genes related to the genetic predisposition to rheumatoid arthritis are human leukocyte antigen genes, and there is a certain hereditary predisposition to this disease. Relatives with rheumatoid arthritis or patients with systemic or autoimmune diseases can provide reference clues for the diagnosis of the disease. It should be noted that patients with rheumatoid arthritis do not necessarily pass on the disease to their next generation. It is recommended that patients with rheumatoid arthritis go to the rheumatology and immunology departments of regular hospitals for detailed consultation.