Schistosomal liver disease is divided into acute schistosomal liver disease and chronic schistosomal liver disease, as follows: 1, can be cured: acute schistosomal liver disease, after a full course of anti-schistosomal symptomatic treatment, can be completely clinical cure, not easy to turn chronic. 2, more difficult to cure: chronic schistosomal liver disease, must be a full course of treatment, the amount of anti-schistosomal treatment to be possible to cure. If the manifestation of portal hypertension of liver cirrhosis has already appeared and schistosomes have been completely cleared by treatment, the splenomegaly and esophagogastric fundic varices caused by portal hypertension cannot be recovered, of course, the portal hypertension can be relieved by surgical methods or treated by liver transplantation. Therefore, people who are frequently exposed to seafood or eat raw fish should be checked for schistosomiasis in order to detect and treat it as early as possible to avoid further progress.