Focal proliferative IgA nephropathy is a relatively mild type of IgA nephropathy and can be treated with hormones (such as prednisone acetate).
The pathology of focal hyperplastic IgA nephropathy is characterized by glomerular tethered hyperplasia, and there are usually few crescent production and glomerulosclerosis. Therefore, it is one of the milder types of IgA nephropathy, and the treatment plan should be considered according to the patient’s condition.
In case of patients who develop hematuria of the naked eye or abnormal urinalysis after tonsillar infection, the infection should be controlled actively. Commonly used non-nephrotoxic antibiotics such as penicillin, erythromycin and other drugs, as well as early tonsil removal surgery. Enalapril and valsartan can also be considered to control blood pressure as well as reduce proteinuria.
If there is persistent proteinuria or the above treatment is not effective, hormone therapy can be considered. Prednisone acetate is commonly used. If the disease is severe and cannot be relieved by hormonal therapy, or if the pathologic type suggests massive crescent formation, a combination of immunosuppressive agents (e.g., cyclophosphamide) can be used.
The above drugs need to be used in accordance with the doctor’s instructions, and patients with focal proliferative IgA nephropathy are advised to go to regular hospitals in time to improve the relevant examinations and standardize the treatment in accordance with the doctor’s instructions.