Hanging cephalosporin can not drink alcohol, because it will cause disulfiram-like reaction, that is, cephalosporin will inhibit the normal metabolism of ethanol, resulting in ethanol oxidation to acetaldehyde, can not continue to decompose and oxidize in the human body and lead to acetaldehyde accumulation of toxicity, manifested as tightness of the chest, shortness of breath, laryngeal edema, dyspnea, heart rate increases, blood pressure drops, flushing, sweating, vomiting, drowsiness, and even anaphylactic shock. The severity of disulfiram-like reaction is proportional to the dose of medication as well as the amount of alcohol consumed, and the reaction usually occurs 15-30 minutes after alcohol consumption. In addition to cephalosporin, the commonly used drugs metronidazole, tinidazole, ornidazole, furazoline, and chloramphenicol can also cause disulfiram-like reactions, so alcohol or ethanol-related products, such as alcohol-centered chocolates, hokkien zhengqi water, or treating the skin with alcohol should be avoided during the administration of the drug as well as for 14 days after its cessation.