Liver inflammation and distension despite antiviral treatment should be alerted to unsatisfactory viral control and complications such as ascites, cirrhosis and hepatocellular carcinoma; in addition, it should be differentiated from other abdominal diseases. 1. When the virus control is not ideal, liver inflammation persists, hepatitis causes liver peritoneal damage, which also leads to liver enlargement, thus leading to liver pain; this situation requires timely medical treatment and adjustment of antiviral drugs as prescribed by the doctor. 2. The emergence of complication situations: (1) Ascites: when ascites occurs, patients will have abdominal distension and pain, poor feeding, lower limb edema and other manifestations; they need to be admitted to the hospital to improve the ultrasound examination, and puncture and drain out the ascites if necessary in order to reduce the symptoms. (2) Cirrhosis: when combined with cirrhosis, patients will have clinical manifestations such as abdominal pain, nausea, vomiting, loss of appetite, etc., and need antiviral, hepatoprotective, antifibrotic and other treatments. (3) Hepatocellular carcinoma: clinical manifestations of hepatocellular carcinoma mainly include abdominal pain, jaundice, emaciation, etc. It needs surgery or systemic treatment. (3) Other diseases: as abdominal pain is mostly radiating pain, pain in liver area should be excluded as a result of cholecystitis, gallbladder stones, pancreatitis and other diseases. If the liver pain is repeated, it is necessary to consult a doctor in time to investigate the cause of pain and carry out targeted diagnosis and treatment.