There is a hole in the left breast when you squeeze it hard, but not when you don’t. The treatment should be chosen according to the cause of the disease, physiological observation is enough, and pathologic diseases, such as cystic hyperplasia of the breast, intraductal papilloma, etc., should be treated by medication or surgery. 1. Physiological nipple discharge: mainly seen during pregnancy or breastfeeding, usually no treatment is needed, and it will return to normal after pregnancy or breastfeeding, so it should be observed. 2. Cystic hyperplasia of the breast: it is a disease caused by the imbalance of estrogen and progesterone secretion, and its symptom is not only nipple overflow, but also periodic breast pain, and the nipple overflow is mostly plasma. The main treatment is medication, such as tamoxifen. If the symptoms are more serious and localized mastopexy nodules are formed, localized mastectomy can be considered. 3. Intraductal papilloma: It is a kind of benign breast tumor, the first symptom is often nipple discharge, mostly bloody discharge, the main treatment is surgical treatment, and local mastectomy. In addition, breast cancer and mastitis may also appear similar clinical manifestations, the left breast squeeze a hole in the overflow without squeezing there is no need to consult a doctor in a timely manner, by a professional doctor for judgment and treatment.