One-time radical surgery for perianal abscess is mainly done by removing the internal orifice and the infected tissues in the perianal area during the surgery so as to avoid the recurrence of perianal abscess or the emergence of anal fistula. During perianal abscess surgery, the internal opening must be cleaned out and ligated so that the necrotic area can be dislodged. After the operation, it is also necessary to clean and protect the anus so that the perianal abscess can be cured at once. At the same time, in daily life, patients should pay attention to a light diet, avoid eating some spicy stimulating hot food, eat more high quality protein and vitamins to help promote the healing of postoperative wounds, such as lean meat, eggs, milk, apples, bananas, pears and so on. It should be noted that the hygiene of the perianal area must be kept clean to avoid infection and inflammation of the surgical wound. Drinking plenty of water, keeping the bowels clear and changing underwear frequently will help the recovery of perianal abscesses, thus achieving a one-time cure.