We may not know much about the term hand sweating, but when it comes to sweating all over your hands somehow, I’m sure many of us know it well. The symptoms are excessive hand sweating, especially in the summer, when the hands sweat so much that they drip down, which causes a lot of problems in the daily work and life of the patient. The prevalence of hand sweating is about 1% on average, and up to 3% in the subtropics, with about 12% of patients having a family history of hand sweating. Sweating is the body’s own means of regulating body temperature, when people are nervous and feel stressed, they will naturally sweat more, but if the sweat exceeds the amount needed to regulate the temperature, then it is excessive sweating. Sweating is caused by the body’s sympathetic nerves being in a constant state of hyperactivity. The symptoms of hyperhidrosis include excessive armpit sweating, foot sweating, and head sweating, while hand sweating is one of the more common types of hyperhidrosis. In terms of the cause of hand sweating, it can be divided into primary hand sweating and secondary hand sweating. Secondary hand sweating occurs after certain diseases, such as hyperthyroidism, menopausal syndrome, mental disorders, and during certain endocrine treatments, which can increase hand sweating. Primary hand sweating is caused by sympathetic hyperactivity and is more common than secondary hand sweating. In the past, hand sweating was not considered a disease, but now more and more people are beginning to have higher demands on their lives, so more and more people are coming to the clinic, paying more attention to their manners and the impression they make on people in social situations, avoiding social embarrassment because of sweaty hands. The current thoracoscopic thoracic sympathetic nerve dissection carried out in some large hospitals is lightly traumatic, well exposed, accurately positioned, safe and reliable, fast recovery, satisfactory and long-lasting efficacy, and can be done bilaterally at the same time, which patients with hand sweating are happy to accept. Nowadays, thoracoscopic thoracic sympathetic nerve trunk dissection has become a better treatment for hand sweating, and the patient’s excessive sweating symptoms disappeared immediately after surgery, and he was discharged from the hospital in 4-5 days with few complications. After the postoperative follow-up, patients are discharged from the hospital and can immediately participate in their normal work and study.