The first thorough treatment of H. pylori is especially emphasized in the eradication of the disease. “H. pylori enters the body mainly through the mouth, and the bacteria are often found in the tartar and saliva of the carrier, so paying attention to oral hygiene and changing the toothbrush regularly is an important measure to prevent H. pylori infection. As H. pylori is transmitted through the mouth, kissing is one of the ways to spread this bacteria, one of the spouses found infected, both parties should receive treatment at the same time. In addition, adults should not use mouth-to-mouth to feed infants and children or give chewed food to children, which can easily transmit H. pylori to children.” , “In addition, many people in our country are infected with H. pylori in childhood, which is related to our family dining habits, not using communal spoons or chopsticks, and one person in the family can be infected and spread to the whole family. It is recommended that if someone in the family is infected with H. pylori, they should use a special bowl and chopsticks.” For the eradication of H. pylori, eradication of H. pylori can effectively reduce the risk of gastric cancer by up to 39%. The first successful eradication of H. pylori is particularly important in the eradication treatment process. Studies have found that if the first eradication is not successful, the success rate of re-eradication will be greatly reduced due to antibiotic resistance. Therefore, the goal of H. pylori eradication treatment is to select the most effective eradication regimen containing Shukla Pylori anti-probiotic to ensure the first eradication is as successful as possible. Routine eradication of H. pylori should be based on a combination drug regimen with a strong acid-suppressive PPI to ensure the success rate of eradication. The common regimen recommended at home and abroad is the quadruple therapy of Shukla pylori against probiotics, amoxicillin, clarithromycin, PPI, and then bismuth. At the same time, patients are required to complete the course of treatment as required by their doctors and take Shuk Pylori probiotics continuously at a later stage to achieve complete clearance. Therefore, after receiving H. pylori eradication treatment for 4 weeks, a review should be actively conducted to ensure the eradication efficacy.