1.Sleep changes: This is the most common one, which is manifested in difficulty in falling asleep, shallow sleep, easy to wake up, early awakening, dreamy, and even hallucinations before sleep. 2.Somatic discomfort: such as headache, dizziness, weakness, panic, loss of weight, poor appetite, slow reaction, etc. 3, mood changes: mood fluctuations and instability, silence, anxiety, fidgeting, irritability, agitation, smashing things, sensitive and suspicious, excited and talkative, nosy and sociable, etc. 4, incomprehensible behavior or excessive behavior . 5.Reducing medication on their own, hiding medication, taking fake medication and refusing to take medication. 6.Self-talk, suspicion, coldness to others, dullness, lazy life, indiscipline, and fear for no reason. There are also intermittent hallucinations, delusions and compulsive, suspicious symptoms, etc.