Negative hepatitis A antibody means no hepatitis A virus infection. Hepatitis A virus can cause viral hepatitis A, an acute infectious disease with liver damage, loss of appetite, anorexia, and abnormal liver function as the main clinical manifestations. Hepatitis A is mainly transmitted through the gastrointestinal tract, and outbreaks can be caused by water or food contaminated with the virus, and daily contact is mostly disseminated cases. Hepatitis A is highly transmissible and has an acute onset, with acute patients and latent infections being the main sources of infection. Hepatitis A has an acute onset and causes acute hepatitis, which does not progress to chronic hepatitis. According to the presence of jaundice, it can be divided into acute jaundiced hepatitis and acute non-jaundiced hepatitis. Acute jaundiced hepatitis mainly manifests as yellow staining of skin and sclera. Hepatitis A is a self-limiting disease, so it can usually be completely recovered, and the main treatment is to pay attention to rest and increase nutrition.