UTIs due to diabetes currently account for 43.8% of all UTIs in the U.S., and this percentage is increasing in China. 2005 U.S. treatment costs for UTIs alone were as high as $32 billion! It is evident that uremia brings a heavy economic burden to patients, families, and even society. It is common knowledge that diabetes will be complicated by cardiovascular disease, but it is often overlooked by the public that diabetes is also likely to be complicated by kidney disease. In fact, diabetes is a systemic vascular disease, and the kidney is mainly composed of blood vessels, so the kidney cannot be spared when diabetes causes vascular disease. Diabetic nephropathy is divided into 5 stages, the 1st and 2nd stage cannot be detected by ordinary non-invasive examination, and the diabetic nephropathy that is detected now is often the 4th and 5th stage, when the patient has obvious edema, large amount of foamy urine, stubborn hypertension, and has entered the irreversible kidney failure stage, and even has entered the uremic phase. At this time, the treatment is difficult and ineffective, and eventually most patients must receive dialysis treatment! Second, the importance of early detection and early treatment early detection of diabetic nephropathy and timely professional treatment is crucial! Early detection of diabetic nephropathy two major assets: regular monitoring of urine microalbumin and glomerular filtration rate! However, this can only send stage 3 diabetic nephropathy, but it is possible to avoid uremia by treating stage 3 diabetic nephropathy aggressively. At present, less than 10% of patients with diabetic nephropathy can be detected in stage 3! And stage 3 is the watershed of treatment. Third, how to detect stage 1 and 2 diabetic nephropathy, there are new studies that the prevention and treatment of diabetic nephropathy should start from stage 1 and 2, and the only way to diagnose stage 1 and 2 diabetic nephropathy is by kidney puncture biopsy, and kidney puncture biopsy can also detect the possibility of diabetes combined with nephritis, so we, the public, should change the concept of early application of kidney puncture biopsy means to diagnose diabetic nephropathy! Fourth, the treatment of diabetic nephropathy active control of blood sugar, blood pressure up to standard is the most critical measures to treat diabetic nephropathy! Other include: reasonable high quality protein diet, control of blood lipids, timely dialysis replacement therapy, standardized Chinese medicine treatment, etc. 5, diabetic nephropathy patients health care common sense 1, hypoglycemia is far more harmful than hyperglycemia; 2, pay attention to self-protection, as far as possible to avoid all infections, fever; 3, avoid staying up late and heavy physical labor; 4, reasonable quality protein diet, low salt, quit smoking; 5, avoid nephrotoxic drugs, common are: antipyretic analgesics, nephrotoxic antimicrobials, nephrotoxic oral hypoglycemic drugs, aristolochic acid class Chinese medicines (mucuna pruriens, mucuna pruriens), etc.; 6. Avoid nephrotoxic examinations, such as enhanced CT examinations.