Two-thirds of gastrectomized patients can take iron supplements by mouth (ferrous succinate tablets, etc.) or eat iron-rich foods (pork liver, lean meat, etc.), or by intravenous iron supplementation (iron sucrose injection, etc.). The main parts of the body that absorb iron are the duodenum and the upper part of the jejunum. A two-thirds gastrectomy will remove the patient’s duodenum, but the upper part of the jejunum can continue to absorb iron, but the absorption of iron may be less than normal. Therefore, patients with two-thirds gastrectomy can be treated with iron supplementation through oral medications such as ferrous succinate tablets and ferric protein succinate oral solution, as well as iron supplementation with more iron-rich foods such as lean meats, pork liver, pig’s blood, spinach, etc., but the rate of iron supplementation is slower. Can also be injected intravenously iron sucrose injection for iron supplementation, iron supplementation speed, but need to pay attention to the infusion to prevent iron sucrose extravasation. Because iron sucrose injection is irritating to the skin, it may lead to localized skin redness, swelling, pain, and in severe cases, it may lead to skin ulcers. Iron supplementation therapy for gastrectomy patients needs to be carried out under the guidance of doctors.