Post-radiotherapy pain needs to be treated with dexamethasone, skin protectants, gastric mucous membrane protection drugs and analgesic drugs according to the cause of pain. 1. Dexamethasone: If the pain is caused by brain edema after radiotherapy, hormonal drugs such as dexamethasone or mannitol can be used to reduce swelling and blood pressure. 2. Skin protectants: Radiation will also cause some damage to human skin, thus causing pain, which needs to be sterilized, and then use triethanolamine cream, clindamycin phosphate gel, mupirocin cream and other skin protectants, antibiotic treatment. 3. Gastric mucosal protection drugs: abdominal pain caused by gastrointestinal mucosal injury, need to take gastric mucosal protection drugs, such as colloidal bismuth pectin, aluminum hydroxide tablets. 4. Analgesic drugs, such as local or generalized pain is more serious, but also need to use morphine extended-release tablets and other analgesic drugs. It is recommended that patients consult a doctor in a timely manner, under the guidance of the doctor for treatment, so as not to delay the condition.