Overall, Metoprolol Tartrate Tablets have a high safety profile. Some patients may be sensitive to the drug or may experience bradycardia during the administration of the drug, which can be reduced or discontinued at this time. Some patients may have bronchial asthma or chronic obstructive pulmonary disease, which may aggravate airway spasm after taking metoprolol tartrate tablets. For people with severe hepatic or renal insufficiency, there is no need to adjust the dosage of metoprolol tartrate tablets. In the case of patients with portal vena cava anastomosis, the dose generally needs to be reduced a little. There are some patients who have a high degree of AV block or have cardiac conduction problems that may be aggravated by taking metoprolol tartrate tablets, but for people who already have a high degree of AV block, they should not go on metoprolol tartrate tablets.