Serum homocysteine is a blood test that generally checks the level of homocysteine in the serum and has some clinical significance for patients with hypertension and cerebrovascular disease. In hypertensive patients, if there is also elevated serum homocysteine, it can be diagnosed as H-type hypertension and the patient can take oral compound antihypertensive drugs specifically for the treatment of H-type hypertension. If a cerebrovascular patient has a high serum homocysteine level, the patient is considered to be at a higher risk of stroke and is advised to actively supplement folic acid and vitamin B12. The patient’s diet should also include more fresh vegetables and fruits, such as celery and spinach, and should be monitored regularly. If the gastrointestinal function of the elderly is poor, it can also lead to poor absorption of folic acid and vitamin B12. It is recommended to treat the cause of the disease, and the patient is also advised to have an outpatient review in six months to a year.