Liver lymph node enlargement of 8 centimeters may be caused by hepatitis, metastasis of hepatocellular carcinoma, cholangitis and so on. 1. Hepatitis: Hepatitis B virus infection, liver worm parasitism, frequent use of hepatotoxic drugs, etc. can cause hepatitis, during which the hilar lymph nodes will secrete immune cells to participate in relevant inflammatory reactions, thus causing swelling of hilar lymph nodes. 2. Hepatocellular carcinoma metastasis: this kind of condition is mostly seen in the middle and late stages of liver cancer, and lymph node metastasis is easy to occur in this period, and when the metastatic site appears in the lymph nodes of hepatoportal, the lymph nodes of hepatoportal will be enlarged. 3. Cholangitis: Inflammation of the gallbladder or obstruction of the bile duct will cause cholangitis, and since the bile duct is connected to the hepatic duct, the related inflammation will spread upward to the hepatic hilum along the channel, which will result in the enlargement of hepatic hilum lymph nodes. It is recommended that people with this condition should go to the hepatobiliary surgery department of the hospital as soon as possible for consultation and treatment.