HPV, or human papillomavirus, is one of the most common pathogens of sexually transmitted diseases, especially in gynecology, causing external genital warts, cervical intraepithelial neoplasia, and, in some cases, cervical cancer with persistent HPV infection. The cervical cancer (HPV) vaccine is a preventive vaccine against the high-risk HPV virus subtypes that cause cervical cancer. The best age for HPV vaccination is 11 to 12 years old, and it is ideal for people aged 9 to 26 years who are not sexually exposed, and for people who are sexually active but not infected with HPV. The quadrivalent vaccine has been proven in large clinical studies to be ideal for women aged 24 to 45 years.