Ebola virus disease is an acute hemorrhagic infectious disease caused by the Ebolavirus (EBOV) of the family Filoviridae. The main clinical manifestations are acute onset, fever, myalgia, hemorrhage, rash, and hepatic and renal impairment. The disease is a multi-organ damage disease, mainly affecting the liver, spleen and kidney, incubation period of 3 to 18 days, the main clinical manifestations are sudden onset, fever, severe headache, muscle and joint pain, and sometimes abdominal pain, the onset of 2 to 3 days may appear nausea, vomiting, abdominal pain, diarrhea mucus stool or blood stool, diarrhea can last for several days, the course of the disease 4 to 5 days into the extreme phase, fever persists, there are changes in consciousness, such as delirium, drowsiness, this phase of bleeding is common. The disease can be followed by a hemorrhage, black stool, injection site bleeding, nasal bleeding, hemoptysis, etc. Pregnant women may experience miscarriage and postpartum hemorrhage, and a measles-like maculopapular rash may appear on the trunk and spread to all parts of the body in 6 to 7 days. Most patients have asymmetric arthralgia, which may be wandering, mainly involving large joints, and some patients have myalgia, malaise, septic mumps, hearing loss or tinnitus, conjunctivitis, monocular blindness, uveitis, and other delayed damage. There are some asymptomatic infections in EHF outbreak epidemics with the presence of EBOVIgG in the serum. The epidemiological significance of asymptomatic infections is not significant because their viral levels are low and the infection is cleared by the effective immune response of the body in a short period of time, and the inflammatory response can disappear rapidly within 2-3 days, thus avoiding fever and tissue organ damage.