An enlarged pancreas needs to be treated with fasting and antibiotics and, if necessary, surgical removal. Many people have an enlarged pancreas caused by an attack of acute pancreatitis, which requires blood tests. Patients with pancreatitis should be prohibited from food intake, and intravenous injections of octreotide should be used to inhibit pancreatic gland secretion and reduce the progress of pancreatic self-digestion, and antibiotic drugs should be used to control the infection after the condition is controlled. Some of the pancreatic enlargement is caused by pancreatic cyst or pancreatic cancer, the condition needs to be observed, and if necessary, the enlarged pancreatic area can be removed surgically, and some patients need to be supplemented with radiotherapy and chemotherapy after surgery to inhibit the spread of the tumor. After surgery, patients should go to the hospital for regular checkups and avoid eating foods with too much fat content in their future lives, as this may induce disease attacks.