Elderly people’s blood creatinine 114μmol/L is seen in physiological increase such as after strenuous exercise or large amount of meat consumption, which is generally normal and does not require special treatment; it is seen in pathological increase, such as acute and chronic glomerulonephritis, chronic renal failure, nephrotic syndrome, diabetic nephropathy, hypertensive nephropathy and other diseases resulting in renal insufficiency, which is abnormal and needs to be paid attention to. The normal reference value of blood creatinine for adult male is 53～106μmoI/L, the normal reference value of blood creatinine for adult female is 44～97μmol/L, and blood creatinine of 114μmol/L for the elderly is out of normal range. 1. Physiological increase: commonly seen after strenuous exercise or large amount of meat consumption, at this time is generally normal, without special treatment, remove the causative factors can generally return to normal. 2. Pathological increase: common in acute and chronic glomerulonephritis, acute and chronic renal failure, nephrotic syndrome, diabetic nephropathy, hypertensive nephropathy, lupus nephritis, heart failure, dehydration and other diseases, this time is abnormal, need to consult a doctor in time, comply with the doctor’s instructions for reasonable and standardized diagnosis and treatment. When abnormal blood creatinine is found, it is recommended that the patient should consult a doctor in time and clarify the cause under the doctor’s guidance, and actively standardize the treatment.