When pediatric viral infectious stomatitis occurs, it is difficult to diagnose the disease because the danger to the child begins with the usual symptoms as well. Then, a detailed examination program is necessary to confirm the diagnosis of the disease. Please see below for more information about the tests for this disease. The following tests can be performed to clarify the diagnosis: a. Routine blood test: Routine blood test is one of the most basic laboratory tests in clinical practice. Routine blood tests include red blood cells, white blood cells, hemoglobin and platelet count. Routine blood is collected by needle prick method from finger blood or earlobe end blood, and after dilution, it is dropped onto a special calculation plate and then placed under a microscope to calculate the number of blood cells. Generally normal, a few may have increased peripheral blood leukocytes. Cytologic examination: A smear was taken from the skin and mucosal herpes and examined for multinucleated giant cells and eosinophilic inclusions in the nucleus. Virus culture: The development of virus research is often closely related to advances in virus culture and detection methods, especially in crested animal viruses, mouse and chicken embryo inoculation, tissue culture, ultracentrifugation, gel electrophoresis, electron microscopy and immunoassay techniques, which have had a profound impact on the development of virology. Herpes simplex virus isolation and culture is more successful, many tissue culture methods can be applied, and it is advisable to take fresh herpes fluid for inoculation. IV. Determination of serum antibodies: With neutralization, complement binding or indirect immunofluorescence tests, patients have more antibodies in their sera. V. Histopathological changes: The pathological changes of recurrence and primary infection are the same, with cellular degeneration and necrosis predominating. The epidermal cells undergo balloon degeneration, reticular degeneration and coagulative necrosis, and the epidermis is loosened and blisters are formed, because balloon degeneration is more obvious and mostly occurs at the bottom of the blisters, so the blisters are often unicompartmental, and intraepidermal blisters can eventually develop into subepidermal blisters. A few reticular degeneration can be seen in the blister wall, sometimes with nuclear division and epithelial multinucleated giant cells. Erythrocytes and neutrophils can be seen in old blisters. Intranuclear inclusion bodies were seen in the invaded cells, which were basophilic and Feulgen positive in the early stages but became eosinophilic and Feulgen negative in the later stages. EEG: EEG is a modern auxiliary examination method to help diagnose diseases by amplifying and recording the brain’s own weak bioelectricity into a curve through an EEG tracer. It is non-invasive to the person being examined. No special tests are usually needed, and if necessary, EEG and other tests can be done in children with convulsions. If the patient has undergone the above tests, he or she will have a good grasp of the accuracy of the test results and will be able to provide a good basis for diagnosis. Finally, I wish the children a healthy growth and the affected children can recover soon!