It is mostly seen in children under 6 years old, especially from 6 months to 2 years old, and is mostly primary. At the beginning, there are fever, headache, general discomfort and other pioneer symptoms, and after 2 to 3 days, the oral cavity starts to show symptoms, initially the oral mucosa is congested in sheets, followed by clusters of small blisters, the blisters quickly rupture, forming small superficial ulcers, about 1 to 2 mm in diameter, the ulcers can fuse with each other to form larger ulcers with multi-ringed edges, covered by pseudomembranes, the submaxillary lymph nodes are enlarged, the child cries, refuses to eat and salivates because of pain. The disease usually lasts 1 to 2 weeks, and some lesions extend to the gums, the gum edge is red and swollen and bleeds easily, and even small ulcers appear, also known as herpetic gingivostomatitis treatment. I, systemic treatment: 1, the plate of root preparations; 2, virus spirit; 3, body timely supplementation of vitamin C and vitamin B complex, etc.; 4, the recurring authors available transfer factor, levamisole, interferon and other treatment. Second, local treatment Keep the mouth clean, can apply 2.5% gentamycin glycerin, 2% tetracycline solution, herpes net (0.1% eye drops), adults can paste a variety of anti-inflammatory film, the pain is severe with 2% lidocaine solution gargle.