Lobular carcinoma of breast is not highly malignant in general and has a better prognosis. There are lobular carcinoma in situ and invasive lobular carcinoma. Lobular carcinoma in situ is non-infiltrative, which simply means that the lobular structure still exists and the cancer cells have not invaded the outside of the lobule, so lobular carcinoma in situ is generally of lower risk. Breast invasive lobular carcinoma is infiltrated from lobular carcinoma in situ to the interstitium, but research shows that breast invasive lobular carcinoma has a better prognosis among invasive carcinomas, and it mainly occurs in postmenopausal women aged 50-60 years old, with a large size of tumor, and it is common to see the involvement of both breasts. However, it is necessary to confirm its malignant rate and treatment according to the size of the tumor, the metastatic degree, and molecular typing. Finally, it is recommended to keep optimism, follow the doctor’s instructions to further improve the examination, choose the appropriate treatment, and actively cooperate with the treatment.