Nowadays, many young people think that only the elderly can get atherosclerosis and coronary heart disease. They are still very young and strong, so they relax their attention to this kind of disease. Atherosclerotic cardiovascular disease. In fact, there is a specialized name for this type of disease called atherosclerotic cardiovascular disease (ASCVD). It is a general term for a group of diseases involving the whole body due to atherosclerosis, mainly including coronary atherosclerotic heart disease, atherosclerosis-originated stroke or transient ischemic attack and peripheral arterial disease, etc., which is the main cause of disability and death from cardiovascular diseases. What is atherosclerosis? Atherosclerosis is the biggest health killer of our time, the common pathological basis of cardiovascular and cerebrovascular diseases, and an important cause of death in patients. Its pathogenesis is complex, and there are many related theories, the earlier ones include lipid infiltration theory, hemodynamic theory, middle smooth muscle cell proliferation theory, endothelial damage theory, inflammatory response theory and so on. Currently, the recognized initiating factors of atherosclerosis are vascular endothelial cell injury and lipid metabolism disorders. Patients with hypertension are at higher risk of atherosclerosis. The combination of hypertension and other risk factors will synergistically exacerbate the development of atherosclerosis, so the incidence of atherosclerosis in patients with hypertension is much higher than that in people with normal blood pressure. The Pathophysiological Determinants of Atherosclerosis in Young Adults (PBDAY) study enrolled 1,277 young adults aged 5-34 years who died of traumatic injuries at 18 clinical centers in 15 countries around the world to evaluate the relationship between cardiovascular risk factors and atherosclerosis. The results of the study showed that atherosclerosis was found in up to 50% of young hypertensive patients . Among the hypertensive population, the prevalence of atherosclerosis was significantly higher compared with those with normal blood pressure (39% vs. 11% in the thoracic aorta, 49% vs. 14% in the abdominal aorta, and 54% vs. 20% in the right coronary artery; P < 0.001). Atherosclerosis is not exclusive to old age. In fact, as early as 1953, during the Korean War, U.S. researchers on the clinical absence of coronary artery disease manifestations of U.S. soldiers killed in action autopsy study found that a significant number of the deceased heart has been coronary artery early lesions, their average age is only 20 years old. 1975, the Vietnam War on the bodies of U.S. soldiers killed in action and repeated the study, at this time, autopsy of the soldiers of the average age of 22 years. The average age of the autopsied soldiers was 22 years old. Surprisingly, 12 years later, signs of coronary artery blockage had risen to 55%. So, atherosclerosis starts from the moment we are born, and atherosclerotic cardiovascular disease is not exclusive to old age. Therefore, we should realize that the age of onset of atherosclerotic cardiovascular disease has advanced under the effect of various comprehensive factors, and we should prevent, diagnose and treat it early.