Mesalazine suppositories and tablets are used in different parts of the ulcerative colon. If the lesion is confined to the rectum, suppositories can be applied, and if the lesion involves a large range of the left half of the colon or the whole colon type, tablets are suitable, which need to be used under the guidance of a doctor according to the condition. Mesalazine is a kind of anti-ulcer drug, its efficacy mainly acts on the inflammatory mucosa of the intestinal tract, inhibits the synthesis of prostaglandins, thus playing a significant anti-inflammatory effect, especially effective on the inflamed connective tissues, but it usually causes adverse reactions. Use with caution in hepatic and renal insufficiency; use with caution in pregnant and lactating women; not suitable for children under two years of age. It is contraindicated in patients with gastric and duodenal ulcers. From the clinical response, the efficacy of Mesalazine Suppositories and Mesalazine Tablets is not similar, they are just different forms, different ways of taking, different prices, when taking can go to the hospital to listen to the doctor’s advice to choose, suitable for themselves. Medications need to follow the doctor’s advice, can not be taken blindly, if you are healthy, do not take drugs casually.