When Sacubitril valsartan sodium is used in the treatment of chronic heart failure and other diseases, it is usually required to take the drug for a long period of time, and the specific time of discontinuation of the drug needs to be based on the doctor’s instructions. When taking the drug, care should be taken to avoid contraindications, and adverse reactions should be monitored. When using this drug, it is recommended to use the drug regularly to avoid dosage reduction or omission. In the course of taking the drug, if abnormal edema, hypotension, drug-induced renal insufficiency, blood potassium abnormality and other adverse reactions occur, it is recommended to go to the hospital in time. The use of the drug is prohibited in the case of hypersensitivity to the components of the drug, taking angiotensin-converting enzyme inhibitors such as captopril, angioedema, taking aliskiren, severe hepatic insufficiency, cirrhosis, cholestasis, pregnancy and so on. Sacubitril valsartan sodium should be used under the supervision of a clinician, unauthorized use of the drug is prohibited.