Enalapril maleate and valsartan capsules can be combined need to be divided into circumstances, simple hypertension is generally not recommended, if used in the treatment of hypertension chronic congestive heart failure can be combined. Enalapril belongs to the angiotensin-converting enzyme inhibitor (ACEI), valsartan belongs to the angiotensin II receptor antagonist (ARB); the two drugs have similar antihypertensive mechanism, can be used for the treatment of hypertension, the combination of drugs will not play a better antihypertensive effect, so it is generally not recommended that the combination of treatment of simple hypertension. Both have similar adverse effects such as headache and dizziness, fatigue, cough, nausea, and upright hypotension, but studies have shown that enalapril in combination with valsartan can be used to treat hypertensive chronic congestive heart failure with better efficacy than enalapril alone, and the two may be combined in such cases, but attention should be paid to the development of hyperkalemia. Treatment with enalapril maleate is contraindicated in people who are allergic to enalapril maleate or other ACEI drugs, renal artery stenosis, post renal transplantation, and primary aldosteronism; treatment with valsartan is contraindicated in people who are allergic to valsartan, pregnant and lactating women, hepatic insufficiency, liver cirrhosis, and severely impaired renal function. Patients who need to combine enalapril maleate and valsartan for treatment are recommended to consult a professional physician and follow the doctor’s instructions.