Sore throat may be caused by acute pharyngitis, acute tonsillitis, acute epiglottitis, etc. If it is caused by bacterial infection, you can usually take levofloxacin. 1. Acute pharyngitis: it may be caused by viral or bacterial infections, viral infections do not need to take antibiotic drugs such as levofloxacin. If it is caused by bacterial infection, you can take levofloxacin if you are allergic to penicillin, cephalosporin, macrolides and other antibiotics. 2. Acute tonsillitis: usually caused by viral or bacterial infections, if it is clear that it is caused by sensitive bacterial infection through secretion culture and drug sensitivity test, you can take levofloxacin. 3. Acute epiglottitis: mostly due to bacterial infection, you can take levofloxacin, but most of the time you need to take intravenous infusion treatment. Sore throat must be guided by the doctor to use drugs, the patient can not self-medication, especially levofloxacin and other quinolone drugs, pregnant women, lactating women and children can not be used.