Many small holes on the soles of the feet can be associated with fossa keratolysis, corns, fungal infections and other causes. 1. Keratolytic dystrophy: mainly caused by infection of rod-shaped bacillus, resulting in superficial plantar skin diseases. It is manifested as a transparent hollow hole like a hornet’s nest, with white skin on the bottom of the foot and a foul odor. 2. Corns: when the local skin is subjected to long-term friction and extrusion, it causes the proliferation of the stratum corneum, which is embedded in the skin and protrudes into the dermis, thus compressing the nerve endings and causing obvious pain. At the same time, the soles of the feet can appear white hollow holes. 3. Fungal infection: Mostly caused by dampness, sweating and fungal infections, resulting in blisters and pimples on the soles of the feet, when the blisters burst, it will make the local epidermal defects and appear a lot of white holes. A lot of holes in the soles of the feet may have other causes, and we recommend that you go to the dermatology department of the hospital to clarify the cause of the disease and facilitate the treatment. Pay attention to wear loose and breathable shoes, pay attention to foot hygiene, change shoes and socks, keep the feet dry and clean.