Engel, a professor of psychiatry and internal medicine at the University of Rochester, New York, USA, proposed in 1977 that the biomedical model should be replaced by a biopsychosocial model of medicine. He pointed out that the biomedical model, which focuses on the biochemical factors that cause disease and ignores the social and psychological dimensions, is a simplified and approximate view. He criticized the limitations of the modern medical, or biomedical, model, pointing out that this model has acquired the status of dogma and cannot explain and solve all medical problems. For this reason, he proposed a new model of medicine, the biopsychosocial model of medicine. From a physiological perspective, estrogen protects women’s blood vessels, improves their elasticity, lowers blood pressure, increases good cholesterol in the blood and lowers bad cholesterol, making women’s blood vessels less prone to sclerosis and blockage. However, after menopause, the estrogen in women’s bodies decreases dramatically, and the heart and blood vessels lack buffering adaptability, so the incidence of cardiovascular disease rises sharply. There are also some female diabetic patients because of nerve degeneration, less sensitive to pain. Some surveys have concluded that women’s blood vessels are more fragile and easily damaged, and that the rate of vascular hardening is faster and the repair function is poorer, all of which may be part of the reason why women have more serious heart disease than men. More likely to suffer from cardiovascular disease, and once suffering from heart disease, the condition are more serious. In addition, Eastern women are often afflicted by unexplained coronary artery inflammation, known as Takayasu’s disease, which is also responsible for women having heart attacks before menopause. From the psychological point of view, observe, for example, obviously heart disease symptoms, women usually do not associate themselves with possible heart disease because of this, and women usually go to the hospital later than men after heart attack, because women do not think they have heart attack, especially after menopause, and many people take some symptoms that may be heart disease, such as chest tightness, walking and wheezing, heart thumping, as inevitable phenomenon of menopause Many people treat symptoms such as tightness in the chest, shortness of breath, and a thumping heart as inevitable during menopause and ignore the fact that they may be heart alerts. Surveys have also found that not only do women not know their own hearts, but doctors are sometimes unable to understand women’s “hearts”. In doctors’ experience, women are more likely than men to complain of chest tightness, but some of this is psychological and not a real heart problem. There are also the opposite cases, these women are very good at holding back, often delayed until the condition is serious before coming to the doctor. There are also women with angina whose symptoms may not be as typical as those found in medical textbooks. On the other hand, some doctors have found that a higher percentage of women without heart disease have abnormal ECGs. Although after menopause, women have higher risk factors for heart disease and a higher mortality rate than men, that doesn’t mean that women don’t get heart disease before menopause, they just have a lower chance. From a sociological perspective, post-menopausal women face challenges in changing status in the workplace and in changing roles in their family status. In the work environment, women after 50 years old either accumulate rich experience in their work to open up a wider world to show their talents and abilities, and take up more important responsibilities in politics, workplace, business and other social fields, and work pressure increases, or they face the prelude of withdrawing from social activities and returning to their families; in the family life environment, most women after 50 years old face In the family life environment, most of the women after 50 years old are facing the process of transformation of romantic to calm and simple to complex family roles. All these unpredictable causes may become potential stressors of different degrees, and the different degrees of stressors occurring in each individual are a series of damages to the cardio-vascular system. On top of this, a complex mix of bio-psycho-social factors come together to invade and create the basis for the high incidence of cardiovascular and cerebrovascular diseases in this period.