There is no such drug as Si Reverse Pill, so it cannot be compared with Si Reverse San. Si Reverse San has the efficacy of dispersing depression, dredging the liver and regulating the spleen. Si Reverse San is composed of Radix Bupleurum Chinense, Radix Paeoniae Alba, Citrus Aurantium Citri Reticulatae and Radix et Rhizoma Glycyrrhizae Praeparatae. It is used in treating symptoms of Yang Depression and Syncope (poor functioning of yang qi leading to coldness of the limbs), which may be characterized by lack of warmth in the hands and feet, or abdominal pain, or discharge of fluid with heaviness underneath, or Liver-Spleen Disharmony (inability of liver and spleen to coordinate with one another), which may be characterized by distension of the coarseness of the ribs and muscles and pain in the epigastric region. The adverse reactions and contraindications of this formula are not known. When discomfort occurs, one should consult a doctor promptly and select medication under the physician’s guidance of evidence-based treatment.