The Anhui Zhifei vaccine is generally not available as a new crown booster and requires the patient to follow the program through all three shots. Anhui Zhifei vaccine, clinically a recombinant subunit vaccine, is generally the S protein gene of the virus, integrated into the microorganisms, such as Escherichia coli, followed by a large number of cultures in vitro, when the microorganisms express the S protein of the virus, purify the S protein, and finally make the vaccine. Patients vaccinated with this vaccine do not require a booster shot at this time. New Crown vaccine booster shots are generally additional vaccines that are added mainly to strengthen the immunization effect of the New Crown vaccine and enhance the prevention of the New Crown virus. New coronavirus vaccine booster shots include inactivated new coronavirus vaccine or adenovirus vector vaccine booster shots, mainly for the two-dose inactivated vaccine (Beijing Biological, Beijing Kexing, etc.). Specific vaccination should be based on the notification from the local epidemic prevention department.