Soreness in both shoulders is not cancer in the vast majority of cases. Cancer is a malignancy, and in the case of a malignancy in the shoulder area, it is usually a persistent pain in one shoulder and a lump is palpable. Pain in both shoulders is usually the result of frozen shoulder or arthritis, an inflammatory pain that can cause pain in multiple joints at the same time. Patients are advised to see a specialist joint surgeon to check for problems such as frozen shoulder, rotator cuff injury or arthritis such as rheumatoid arthritis or gouty arthritis. Or maybe it’s just fasciitis in the back caused by working long hours at a desk.