Gallbladder stones can lead to biliary colic and dyspepsia, and there is no effective way to relieve them. Failure to intervene in a timely manner can lead to acute cholecystitis, biliary obstruction, and other diseases. Patients should take general treatment, medication and surgery as early as possible to intervene. 1. General treatment: patients with serious condition should take bed rest and avoid strenuous exercise; for patients with acute attack, fasting can also be taken to cope with it. 2. Drug therapy: patients can apply scopolamine, ibuprofen and other drugs to antispasmodic and analgesic under the guidance of doctors. If considering the combination of infection, should use cefuroxime, moxifloxacin and other drugs for anti-infection treatment. 3. Surgery: For patients with large stones and severe symptoms, laparoscopic cholecystectomy or open cholecystectomy can also be used. Patients with different degrees of illness should consult a doctor to confirm the diagnosis and follow the doctor’s instructions for treatment.